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As we noted in the CY 2026 OPPS/ASC proposed rule, nonexcepted off-campus PBDs currently use the above referenced G codes to report radiation therapy services and, were we to finalize our proposal to delete them, they would no longer be available after December 31, 2025

Sources B vitamins and folic acid (2017) NHS [accessed 18 June 2020] Vitamin B12 Deficiency and Pernicious Anaemia (2016) Patient Info [accessed 18 June 2020] Vitamin B12 or folate deficiency anaemia (2019) NHS [accessed 18 June 2020]

The practical takeaway: AOD-9604 has a clean safety profile in trials but a failed Phase 2b efficacy endpoint

Preservatives can result in hypersensitivity reactions

This can cause heartburn, discomfort, and sometimes require medication or further treatment

Vitamin B 12 deficiency can lead to anemia, neurologic, and digestive dysfunctions