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Conclusion: The outlook for state Medicaid coverage of GLP-1 AOMs While 13 state Medicaid programs covered at least one GLP-1 approved for weight management as of August 2024, states subsequently reversed course: California, New Hampshire, Pennsylvania, and South Carolina recently withdrew coverage

Many patients experience a decrease in appetite and initial weight loss within the first 1 to 2 weeks

Key players today include Mounjaro (tirzepatide) a dual-agonist of GLP-1 and GIP receptors and coming soon, Retatrutide a triple-receptor agonist (GLP-1, GIP and glucagon) that has shown even stronger early results

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This represents a significant convenience advantage over daily injection options like liraglutide (Saxenda)

Tirzepatide has shown robust improvements in blood pressure and fasting lipid levels