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Active GLP-1 protein secondary structure includes two -helices from amino acid position 1320 and 2435 separated by a linker region

doi: 10.1056/NEJMoa2401943 204 SkovJDejgaardAFrkirJHolstJJJonassenTRittigSet al

Changes in any of these should prompt protocol review and possible adjustment

GLP-1 medications may be appropriate for you if you have: Excess weight or obesity (BMI of 27 or higher with weight-related health conditions, or BMI of 30 or higher) Type 2 diabetes or prediabetes Weight-related health conditions (high blood pressure, high cholesterol, sleep apnea) Struggled with traditional diet and exercise approaches Even small amounts of stubborn fat you want to lose Important Contraindications: These medications are not suitable for everyone

NAION is an injury related to reduced blood supply to the optic nerve

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