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Certain populations may need modifications to the dose schedule based on their unique physiological characteristics

Data availability All data from this study are presented in the published article and the supplementary material

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They persist for the entire week between injections because the drug has been engineered for sustained activity

However, GIP immunoreactivity was identified in the adult rat brain using a specific monoclonal antibody against GIP (136), suggesting that while GIP is not expressed in the brain, peripheral GIP can reach the deep brain

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