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[9] Excess caffeine may cause jitteriness, gastrointestinal upset, and sleep disturbance, with individual sensitivity modulated by CYP1A2 polymorphisms and habitual intake
Interestingly, despite the lack of consistent actions of metformin in terms of metabolic profiles, treatment with the insulin sensitizer caused a complete normalization of ovarian cyclicity, pointing to a discernible reproductive effect of metformin in some PCOS conditions, in line with clinical literature 68 , although conflictive results have been reported also 69
ACSS2-mediated acetyl-CoA synthesis from acetate is necessary for human cytomegalovirus infection
A retrospective analysis of rivaroxaban, a factor Xa inhibitor, demonstrated non-inferiority with regard to thrombosis compared to warfarin with the advantage of less outpatient visits and monitoring (ClinicalTrials.gov Identifier: NCT02072668)
Safety and tolerability of the hexadecapeptide AOD9604 in humans
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