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Clinical development of long-acting amylin analogs. ClinicalTrials.gov

In vitro tendon-explant work found BPC-157 significantly increased fibroblast outgrowth, survival under oxidative stress, and migration in a dose-dependent manner, an effect linked to increased phosphorylation of FAK and paxillin Chang et al

This sample size is consistent with prior mechanistic studies and the 3R principles [52, 53], although the relatively small cohort remains a limitation and should be expanded in future work

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Such mechanisms only produce a small amount of free radicals that the body can typically process and eliminate