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Notably, about one in four of these patients did not carry a type 2 diabetes diagnosis , suggesting that a substantial portion of GLP-1 use is being driven by weight loss and other emerging indications outside of diabetes care (Figure 2)
A separate category, including CJC-1295 and Sermorelin, works through growth-hormone stimulation instead of appetite signaling: these peptides prompt the pituitary gland to release more of the body's own growth hormone, which supports fat metabolism and helps preserve lean muscle during a calorie deficit
Of those, more than 65 percent reached a BMI of below 30 within 80 weeks, which no longer classified them as having obesity
The results from these trials were positive and eventually led to Wegovy receiving FDA approval as a chronic weight management medication in June 2021
It is easy to understand why so many people want something that feels less intimidating, with fewer side effects, and easier to fit into daily life
