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GLP-1 agonists upregulate antioxidant enzymes including HO-1 (heme oxygenase-1) and NQO1 (NAD(P)H quinone dehydrogenase 1), providing a counterbalance to the oxidative damage occurring in the pelvis

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Systemic reactions like severe abdominal pain, jaundice, or breathingdifficulty in rare cases

Melanin-like nanoparticles alleviate ischemia-reperfusion injury in the kidney by scavenging reactive oxygen species and inhibiting ferroptosis

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Berson A, Nativio R, Berger SL, Bonini NM