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Manufacturers and clinical guidelines recommend dose adjustments through full-dose modifications rather than splitting individual injections

For each peptide a paired Welch t-test p -value threshold of 0.05 was used to evaluate the significance of abundance variation GPX3 ELISA Following plasma thawing, a large subset of samples collected in 2021 from the discordant sibling cohort ( n = 174) were vortexed briefly and diluted 1:100 in ELISA sample buffer (NOVUS Biologicals)

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While the LAMP1 level in SN TH exhibited no significant difference between HET and WT mice, it was significantly decreased in HOMO mice compared to WT and HET mice (Fig