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Wound healing: Depends on location

These effects have been recently associated with several molecular pathways [10,11,20,58,59,60,61,62,63,64,65,66], in particular with the increased expression and internalization of VEGFR2, and the activation of the VEGFR2-Akt-eNOS signaling pathway [60,61], interacting particularly with the NO [49] and prostaglandins systems [50]

DSIP enhances REM sleep

It is believed to influence levels of dopamine, norepinephrine, and serotonin in the brain key neurotransmitters involved in satiety, mood, and metabolism

Dramatic overnight changes are unlikely, with healing proceeding incrementally

doi:10.18632/oncotarget.11168 Sakuma S, Ishimura M, Yuba Y, Itoh Y, Fujimoto Y