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This decision was made because this review aims to provide a general overview of the current literature landscape and summarize the progress of research in this emerging area, rather than to conduct a formal meta-analysis or systematic review

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Sugimoto et al., 2010

Metabolic Engineering the Zone diet, high-dose omega-3 fatty acids, and polyphenols activates AMPK through three independent, but synergistic pathways to address all three types of inflammation: cytokine-based, eicosanoid-based, and free-radical-based

doi: 10.1111/j.2042-7158.1987.tb07154.x