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Ionomycin significantly increased PS exposure in all conditions when compared to the DMSO control: Ringer (2.4% to 24%, p =0.0004), Ringer+Albumax (0.72% to 22%, p =0.0005), iRPMI (0.63% to 23%, p =0.0003) and iRPMI+Albumax (0.43% to 15%, p =0.0329)

Zhou Y, Khan M, Jiang L, Fu C, Dong Y, Luo L, et al

Efficacy of FLU-v, a broad-spectrum influenza vaccine, in a randomized phase IIb human influenza challenge study

479 Mitochondrial dysfunction disturbs T-cell homeostasis by activating cell death pathways involving Bcl2, OPA1, PHB2, ATG5, OMA1, and SIRT3, while reduced OXPHOS, membrane potential instability, and altered glycolysis further destabilize immune function

Differential Effects of Neonatal Endotoxemia on Heart and Kidney Carnitine Palmitoyl Transferase I

The results of LDSC analysis show weak evidence of a genetic correlation between SLE and ursodeoxycholate ( rg = 0.0395, se = 0.2454, p = 0.8722), taurodeoxycholate ( rg = 0.1601, se = 0.1715, p = 0.3503), N1-methyladenosine ( rg = 0.0427, se = 0.362, p = 0.7538), 1,5-anhydroglucitol (1,5-AG) ( rg = 0.0395, se = 0.0840, p = 0.6383), 1-arachidonoylglycerophosphocholine ( rg = 0.0320, se = 0.1026, p = 0.7554), isobutyrylcarnitine ( rg = 0.1165, se = 0.1219, p = 0.3392), palmitoleate (16:1n7) ( rg = 0.2461, se = 0.1551, p = 0.1124), and 1-oleoylglycerophosphoethanolamine ( rg = 0.1058, se = 0.2077, p = 0.6105), suggesting that the shared genetic component did not confound the MR estimates (Supplementary Table S1)