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Wegovy and Zepbound are injected once weekly, while Saxenda is injected once daily, making it a bit less convenient

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The introduction of biosimilars will increase pricing pressure and challenge the market share of originator brands

Eli Lilly, the company which makes Mounjaro, says "patient safety is Lilly's top priority", and that it "actively engages" in monitoring, evaluating and reporting information to regulators and prescribers.

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Other neuroprotective mechanisms potentially involved in the treatment of cognitive disorders as well as cerebrovascular disease and epilepsy suggest that GLP-1RAs can enhance the viability of neurons and restore neurite outgrowth by stimulating neurotrophic factors, thus increasing subventricular zone progenitor cells, decreasing apoptosis and the level of pro-inflammatory factors, and strengthening the bloodbrain barrier 37