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Most of these were accidental overdoses, where people mistakenly took two doses or took the wrong dose

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Discussion Since the finding that the thiazolidinedione rosiglitazone increased cardiovascular events, much weight has been placed on the safety of novel glucose-lowering drugs

Short answer: It appears tolerable in very limited early human data, but there is not enough evidence to call it safe for general use

Quality and blood sugar Research-use vials are not tested or approved for human use, so purity and contamination are real risks

[6/6] other Porto-systemic shunting, portal vein thrombosis (any shunt that bypasses the liver)