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Bottom Line Newer prescription weight loss drugs like Wegovy, Foundayo or Zepbound can produce dramatic weight loss results of 10 to 20% or more, but come with an initial risk of stomach-related side effects, like nausea, vomiting, diarrhea, constipation or stomach-area pain

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Effects on Lean Mass One of the primary concerns with pharmacologically induced weight loss is the potential for lean body mass (LBM) loss, which includes muscle and organ tissue