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Continue monitoring During GLP-1 receptor agonist therapy, monitor patients for the following signs or symptoms of acute pancreatitis: Weight loss of more than 1.5 kg per week is usually associated with prolonged periods of fasting or anorexia and, as discussed earlier, causes the release of cholesterol into the bile and induces bile stasis

2020 Aug;38:43-49

Stress reduction through meditation or breathing exercises lowers cortisol, which interferes with GLP-1 signaling

Nat Genet (2007) 39(5):596604.10.1038/ng2032 153 SakiyamaTFujitaHTsubouchiH

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It's important to note that tirzepatide is contraindicated in patients with a personal or family history of serious hypersensitivity to tirzepatide or any of the product components