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} Diabetes, obesity, metabolic syndrome, etc are significant macroeconomic concerns

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Seven additional Phase 3 TRIUMPH trials are expected to report results throughout 2026, covering obesity, type 2 diabetes, sleep apnea, chronic low back pain, and metabolic liver disease (ClinicalTrials.gov)

In real-world practice, a SGLT2i and a GLP-1RA are more likely to be initiated sequentially rather than simultaneously, not only for economic reasons but also to improve medication adherence [1]

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