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Before and After Results Clinical trials have shown: 1015% average body weight reduction with semaglutide (dose-dependent) Up to 1522% average weight reduction in some tirzepatide trials Timeline Expectations: Appetite changes: 14 weeks Visible weight loss: 48 weeks Significant results: 36 months Individual results vary based on dose, adherence, diet, activity level, and metabolic health
Updated 9/29/2005
Brain activity in hunger and satiety: an exploratory visually stimulated FMRI study
This effect is called rebound insomnia
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