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Notably, the potential of hydrogen interventions to alleviate non-motor symptoms, such as constipation and sleep disorders, may address the limitations of existing therapies (Pluta et al., 2022)

J Rheumatol 18:394400 Miquel S, Martn R, Rossi O et al (2013) Faecalibacterium prausnitzii and human intestinal health

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while another study including relevant studies up to April of 2022 indicated that lycopene was capable of relieving symptoms of mouth opening and tongue protrusion of patients with OSF, which meanwhile reducing pain and promoting resolution of OLP, exhibiting comparable efficacy as steroids (Al-Maweri et al., 2023)

Hewitt CD, Savory J, Wills MR