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This situation has been mimicked in more recent times when imbibers of moonshine whiskey, often made in radiators containing lead, developed a lead poisoning-associated gout (Saturnine gout)
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It believed that in physiologic conditions when the membrane transporters are saturated, the leak pathway complements the transcellular pathway (active transport) in absorbing water and nutrients (13)
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(2016) A phase I new approaches to neuroblastoma therapy study of buthionine sulfoximine and melphalan with autologous stem cells for recurrent/refractory high-risk neuroblastoma, Pediatr
Hershey Medical Center, United States Reviewed by Oliver Planz, University of Tbingen, Germany
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