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Potent anti-fibrotic agent SalB suppressed autophagosome formation and autophagic flux in HSC by down-regulating the extracellular regulated protein kinases (ERK), c-Jun N-terminal kinase (JNK), and p38-MAPK pathways, leading to decreased expression of light chain 3 II, autophagy-related gene 5 (Atg5), -SMA, and CoI (Jiang et al., 2022)
doi: 10.1210/mend.14.2.0420
Maroon is also Chairman of the Medical advisory board of General Nutrition Centers (GNC)
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Aging and infections As we age, the natural production of glutathione declines
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