Cancer Therapy: Senolytics may be beneficial in cancer treatment by removing therapy-induced senescent cells that contribute to cancer recurrence and resistance
Curr Anal Chem 14(5):512518 Wang R, Yang Z, Zhang J, Mu J, Zhou X, Zhao X (2019) Liver injury induced by carbon tetrachloride in mice is prevented by the antioxidant capacity of Anji white tea polyphenols
Additionally, Nrf2 promotes GSH efflux, which is an unexpected regulator of ferroptosis sensitivity, while Nrf2 inhibition can act synergistically with ferroptosis inducers (Sun et al., 2016a
The cysteines most likely responsible for this thiol sensitivity have been identified [10]
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14,15 The role of glutathione as a potential adjuvant for prevention of chemotherapy induced neurotoxicity has also been evaluated