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Under the acceleration of TGF-1, Nox4 mRNA is significantly upregulated and mediates the transformation of fibroblasts into myofibroblasts by activating TGF-1-Smad2/3 signaling, which leads to cardiac fibrosis

doi: 10.1016/j.dsx.2020.11.004 121

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Alpha-Lipoic Acid (ALA - 6000 mg) & Ascorbic Acid (22000 mg): Help fight free radicals and support skin radiance