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46 ) is a recently reported humanized antibody which efficiently neutralizes both SARS-CoV and SARS-CoV-2

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At the same time, ferroptosis is accompanied by excessive ROS production, resulting in depolarization of the mitochondrial membrane potential and opening of the mitochondrial permeability transition pore (MPTP), further leading to cell rupture (Ravingerov et al., 2020)