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The FDA last week issued warning letters against a handful of companies flagging violations regarding the promotion and sale of unapproved weight-loss drugs, including unlicensed versions of the blockbuster therapies semaglutide and tirzepatide

1 Weight loss of 10% or more can lead to remission of type 2 diabetes and a significant reduction in cardiovascular risk, but achieving and sustaining weight loss with lifestyle interventions alone is difficult

These studies employed sophisticated imaging technology to objectively measure changes in pigmentation, confirming that the improvements observed were not merely subjective perceptions but genuine biological changes in skin structure and coloration