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In order to reduce sugar intake, food industries have been trying to find alternative materials to replace sugars sweet taste with a low-calorie material under the concept of "Sugar Substitution"

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A total of 8184 individuals with obesity or overweight (and one or more weight-related comorbidities) and without T2D initiated obesity pharmacotherapy with a prescription fill for injectable semaglutide or tirzepatide from January 1, 2022, to December 31, 2023

Less common but more serious side effects include pancreatitis (inflammation of the pancreas) and gallbladder problems

The body weight of the patients treated with semaglutide decreased in a dose dependent manner

Reinforces early antioxidant defense