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Clin Ther (2017) 39(9):17809.e33

A unique feature of skeletal muscle, relative to glucose uptake, is that contraction or exercise induces a rapid insulin-independent increase in glucose uptake

Plus, proper hydration keeps the skin elasticity high, so there tends to be lower chances of sagging

Intramuscular injections (IM) directly deliver vitamins, minerals, and amino acids into the muscle, allowing for better absorption and faster results than oral supplements