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Physiologic GLP-1 secretion is a complex, incompletely understood process, with early studies suggesting potentiated release through nutrient supplementation, whole foods, dietary patterns, and microbiome alterations [260,264]
Patients should contact their healthcare provider if they experience severe or persistent heartburn that does not respond to conservative measures or over-the-counter treatments within 1-2 weeks, as this may indicate more significant gastroesophageal pathology requiring investigation
DOI 10.1016/s0140-6736(25)02105-1.
The platform provides ongoing updates on regulatory changes, new medication approvals, and coverage policy shifts that affect who can access GLP-1 therapy
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