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When people are on these medications, all these beneficial things happen: Blood pressure gets better, cholesterol goes down, insulin resistance goes down, says the senior study author, Ziyad Al-Aly, MD, a clinical epidemiologist at WashU Medicine and the chief of the research and development service at the VA Saint Louis Health Care System, both in Missouri

By taking small, frequent meals, staying hydrated, avoiding trigger foods, and following a gradual dosing plan, most people can manage this side effect successfully

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But as GLP-1s continue to surge in popularity, its coming back into vogue

A 2022 systematic review of randomized controlled trials confirms its effectiveness in improving signs of photoaging, including fine wrinkles, skin texture, and collagen formation