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Our drug candidates may prove to have undesirable or unintended side effects, toxicities or other characteristics that may preclude our obtaining regulatory approval or prevent or limit commercial use with respect to one or all intended indications

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Por otra parte, el GLP-1 circulante penetra en reas circunventriculares del SNC como el rgano subfornical, rgano vasculosum de la lmina terminalis, la eminencia media prxima al ncleo arcuato y el rea postrema, merced a la permeabilidad parcial de la barrera hematoenceflica2,3,6

During the entire experiment, the mice were housed under rigorously controlled conditions, including a temperature of 23C 2C, a relative humidity of 45% 5%, and a consistent 12-hour light/dark cycle