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[12] [16] They are active over a wide variety of substrates with considerable overlap

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GHK-Cu focuses on copper chelation, collagen synthesis, and ECM scaffold formation, with the strongest evidence for topical skin and wound-healing applications [1][2]

However, GKT136901 was found to scavenge peroxynitrite, which may complicate the interpretation of results from NOX-inhibitory assays (GKT137831 does not scavenge RS)