If orforglipron is approved along with Novo Nordisk's oral Wegovy (see Oral Wegovy), there will be two oral GLP-1 therapies available in 2026
The Study: Real-World Weight Loss Outcomes Researchers analyzed data from over 50,000 adults with obesity: 38,545 patients received a GLP-1 medication such as semaglutide or tirzepatide 12,540 patients underwent bariatric surgery, primarily gastric bypass or sleeve gastrectomy Key Findings : Surgery patients lost an average of 24% of their body weight over two years about 58 pounds
Singh AK, Gangopadhyay KK, Singh R
Triple-Hormone-Receptor Agonist Retatrutide for Obesity: A Phase 2 Trial PMID: 37366315 N Engl J Med
Protein powders are a great supplement to help with a healthy diet, and they add a great source of lean protein, but the overall diet needs to be full of nutrients
Recommended intakes vary by sex and age