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136 In a randomized controlled trial in 66 participants with mild-to-moderate sleep disorders related to anxiety, subjective measures of time needed to fall asleep, sleep duration, and sleep quality improved in those given 15.5 mg saffron extract daily for six weeks, but not in those given placebo

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While extrapolated data from UK/US, CF clinics suggest a prevalence of 1:12,0001:40,000 among Indian children (95), a 2020 North Indian study revealed a high CFTR mutation carrier rate of 1:22, signaling a potentially higher prevalence (96)