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Its like a rubber bandyou pull it hard and it snaps back quickly. For that reason, clinicians typically counsel patients that GLP-1 medications are a long-term treatment, similar to medications for high blood pressure or diabetes
We then performed two-sample MR and colocalization analyses to estimate the causal effect of GLP-1R-based agonists on MASLD, its metabolic risk factors, and multi-organ complications
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In Phase 1 studies, survodutide was generally well tolerated, with no significant safety or tolerability issues observed in either healthy individuals with overweight or obesity [87, 88]