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Growth, especially muscle hypertrophy, increases resting energy expenditure and can create a calorie deficit

Lovelle asserts

And they can achieve a slow, gradual weight loss, usually over the course of two years, potentially more, and then be seen for weight maintenance

This means you need to push through the initial side effect window to reach the benefit window

[4] Ultimately, the choice of GLP-1 agonist should be a collaborative decision between the patient and their healthcare provider, taking into account individual factors, treatment goals, and potential risks and benefits