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These effects suggest that GLP-1R agonists may mitigate the muscular deleterious effects associated with conditions like idiopathic inflammatory myopathy (68)

Since the coatomer functions to retrieve a wide variety of eukaryotic proteins, it is not surprising that coatomer dysfunction has broad secretory effects and is linked to multiple disorders of growth, development, auto-immunity, and cancers 24,43,44,45,46,47,48,49,50,51,52,53,54

doi: 10.1038/jcbfm.2010.71 53 ConfortiLGilleyJColemanMP

PMID 32633020

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