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The mature adipocytes secrete BMP4 that triggers preadipocyte differentiation by inducing the separation of Wnt1 inducible-signaling pathway protein 2 (WISP2) and zinc finger protein 423 (ZNF423), allowing ZNF423 to translocate into the nucleus and activate peroxisome proliferator-activated receptors (PPAR) and downstream cascade including CCAAT/enhancer-binding proteins (C/EBP), , and [41, 42] ( Figure 1 )

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Intramuscular injection Some researchers prefer intramuscular administration, particularly when combining with training

For this reason, researchers prepare acetic acid water fresh or work from single-use aliquots rather than multi-use vials

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