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Because it primarily remains within the bloodstream and extracellular space, it is often selected for patients needing heavy metal detoxification rather than vascular support

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FIGURE 4 Hence, it is the prevailing recommendation among endocrinologists that non-pregnant individuals with PCOS exhibiting abnormal glucose regulation, irrespective of their body weight status, initiate metformin therapy promptly upon diagnosis, with a prescribed duration of treatment lasting at least 36 months

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