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1c), suggesting that GDH1 knockdown likely limits -KG production and affects cell growth

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shows robust anti-obesity, anti-diabetic, and cardiometabolic effects in preclinical and clinical studies, including significant reductions in body weight, glycemic markers, blood pressure, and lipids 1,3,5

The region plays a significant role in the global market due to its large population, high prevalence of obesity, and well-developed healthcare systems