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Specifically, among treatment agents, Schisandrol A demonstrated the largest effect size, accompanied by a concomitant reduction in heterogeneity [SMD = 2.88, 95% CI (3.41, 2.34), I 2 = 69.3%, p = 0.003]

UK SmPCs note that GLP-1 receptor agonists have been associated with thyroid C-cell tumours in rodent studies, though a causal relationship in humans has not been established

Despite advances in the understanding of disease pathogenesis, and the increased availability of treatment options, the prevalence of ESRD continues to rise in people living with T2DM [6]

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Key risk factors contributing to this increase were obesity and a family history of diabetes, both of which were more prevalent among younger individuals

The six criteria that actually matter Dose density: Can it carry a therapeutically meaningful amount