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Obesity is a severe public health problem that leads to other ailments such as type 2 diabetes, liver disease, cardiovascular disease and hypertension
The most commonly reported relate to digestive discomfort, such as nausea or looser stools, and sometimes a more pronounced body odour
Compounds targeting body recomposition (like growth hormone secretagogues) benefit from IM because rapid systemic distribution is the goal
They also found a significant reduction in fasting plasma glucose, serum insulin levels, homoeostasis model of assessment-insulin resistance and dehydroepiandrosterone sulphate (DHEAS) in the treated patients
In a randomized, controlled clinical study (Study G), adult patients with type 2 diabetes were randomized to 5 years of treatment with once-daily insulin glargine or twice-daily NPH insulin
Doyle and Egan, 2007)
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