[2] [3] This multifaceted mechanism helps improve glycaemic control in people with type 2 diabetes whilst also facilitating weight loss
Clinical priorities may include weight loss, avoidance of hypoglycemia, desired magnitude of glucose lowering, cost, side-effect profile, possibility of pregnancy, and comorbidities [Grade D, Consensus]
However, glucagon also raises hepatic glucose output, which could be counterproductive in type 2 diabetes
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If your side effects are unpredictable, start with evening dosing for the first 4 to 6 weeks as you establish your dose
This guide is part of the PlexusDx Education Hub, our home for GLP-1 science, weight-management protocols, and the genetics that shape metabolic outcomes