Dysesthesia Dysesthesia refers to unusual skin sensations, such as tingling, prickling, burning, or altered sensitivity
GLP-1 : From Diabetes Management to Weight Loss Both Ozempic (the brand name for Novo Nordisks drug semaglutide) and Mounjaro (the brand name for Eli Lillys drug tirzepatide) are GLP-1 (glucagon-like peptide-1) agonists originally designed to help people with Type 2 diabetes
Inactivation of hepatic foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation
When in doubt, always seek clarification before use
Who should not take GLP-1s GLP-1s in all forms are unsuitable for people who: are pregnant or breastfeeding do not meet the eligibility criteria have a family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN2) Medical Perspective Patients with needle phobia, a preference for pill-based routines, or good adherence to oral administration guidelines may be better suited to oral GLP-1 formulations like semaglutide (Rybelsus, Wegovy), which can enhance treatment acceptance and potentially offer strong glycemic or weight control
Raj Dasgupta, MD, FACP, FCCP, FAASM, board-certified in pulmonary, sleep, internal, and critical care medicine and chief medical advisor for Sleepopolis, isnt prescribing GLP-1s, but he will refer OSA patients to an endocrinologist if he believes they might benefit from a GLP-1
