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Administration Routes and Techniques Most GLP-1 agonists are administered via subcutaneous injection, meaning the medication is injected into the fatty tissue just under the skin

Managing constipation Why it happens: GLP-1 medications slow digestion, sometimes leading to constipation, especially if food and water intake decrease

Ozempic is a diabetes drug, but it became a blockbuster in recent years when doctors and patients realized that people who took it lost significant weight

C.Vila-BedmarR.MirasierraM.Cruces-SandeM.VallejoM.JonesB.et al (2021)

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The first person to be successfully treated was Leonard Thompson (figure 7)