Symptoms include pain in the upper stomach, fever, yellowing of the skin or eyes (jaundice), or clay-colored stools
In our experience, a diet focused on high-quality proteins, vegetables, and slow-burn carbohydrates tends to be a healthy and sustainable diet for most patients
Extra weight and high blood sugar both contribute to kidney disease progression, so medications that address these conditions may actually support kidney function rather than harm it
M., Cahoon R
Inhibition of GSK3-mediated BACE1 expression reduces Alzheimer-associated phenotypes
Indications: Overactive bladder Common symptoms include urgency, urinary incontinence, and increased urinary frequency Side Effects: dry mouth constipation QT prolongation urinary tract infection worsening of myasthenia gravis aggravation of decreased GI motility in patients with autonomic neuropathy WARNINGS: angioedema of the face, lips tongue and/or larynx has been reported CNS Effects: agitation, confusion, hallucinations, abnormal behavior & memory impairment in patients taking 5 mg oxybutynin for more than 3 years compared to no use (Thomas & Walters, 2021): increased risk of dementia (adjusted hazard ratio 1.54) increased risk for Alzheimers disease (adjusted HR 1.63) Pharmacokinetics: taken orally by tablet, 5 or 10 mg once daily metabolized by CYP3A4 half life 13 hrs Notes: the estimated Walmart cost for generic oxybutynin is ~$9 for a supply of 30 generic tablets (GoodRx.com
