A Nature Scientific Reports 2016 study showed GHK-Cu had no cytotoxicity to human keratinocytes at concentrations up to 5,800 M over 72 hours and did NOT induce inflammatory biomarkers (IL-1, IL-8, HSPA1A, FOSL1) unlike other copper compounds, concluding GHK-Cu has a low potential of inducing skin irritation
These side effects usually dont last long
Increased collagen production can also aid in wound healing and scar reduction
Advantages and Disadvantages Advantages: Fast spot correction Disadvantages: Can cause irritation Not ideal for sensitive skin Safety Considerations Requires careful usage, especially in hot and humid Pakistani climates
It also encourages the production of collagen, a protein that keeps skin firm and stretchy, and glycosaminoglycans, like super-hydrators for the skin
The timeline is pretty predictable: you might feel slightly tired for the first couple hours as your body processes everything, then experience an energy boost that coincides with that coveted glow