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Among enrolled patients, the mean bodyweight was 99.8 kg (standard deviation [SD] 21.5) and the mean BMI was 35.7 kg/m 2 (SD 6.3)

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The other mouse study reported no difference in offspring weight at birth or maternal weight gain during pregnancy but did observe an increase in pre-weaning fetal growth after maternal exendin-4 (15)

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Guo M, Gu J, Teng F et al (2020) The efficacy and safety of combinations of SGLT2 inhibitors and GLP-1 receptor agonists in the treatment of type 2 diabetes or obese adults: a systematic review and meta-analysis