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and in 2050, there will be 115 million dementia patients [29,30]

Add in potential diarrhea or vomiting during dose adjustments, and mild dehydration is common

For the DIA-PASEF method, we used the Bruker standard short gradient method (m/z range: 4751000 Da, 1/K0 range: 0.851.27 Vs cm 2 , diaPASEF windows: 21 25 Da)