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PMC 4086029

Infant (up to 12 months) 0.5-1.4 ug/day Children (1-15 years) 1.5-4.0 ug/day Women: 4.0 ug/day Pregnant women: 4,5 ug/day Breastfeeding women: 5.5 ug/day Men: 4.0 ug /day The doctor can detect a vitamin B12 deficiency

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With enhancement of target gene expression, it is proposed that NATs can increase the expression of the target gene through increasing the stability of the sense mRNA or euchromatin-associated epigenetic modifications [54]

Tabe Y, Jin L, Konoplev S, Hongbo L, Kimura S, M-B R, Kantarjian HM, Andreeff M , Konopleva M

What is more likely is that you are not getting the right amount or concentration of the drug you either get too little or too much, which could lead to side effects