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RSL3 suppresses spheroid formation and viability, and halts migration of PTC cells in vitro We postulated that the RSL3-mediated suppression of thyroid tumor cell viability is a ferroptosis pathway-dependent process, therefore, we treated K1 cells with a lethal dose of RSL3 alone and in the presence of either a ferroptosis inhibitor Fer1, or a pan caspase inhibitor, Z-VAD-FMK (ZVAD) and measured cell viability

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Toniolo RA, Silva M, Fernandes FBF, Amaral J, Dias RDS, Lafer B

2016;7(2):e00331

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Description Suggested Use Adults: Take 1 capsule daily with a meal providing protein or as directed by your health-care practitioner